分析機器の輸入販売＆コンサルタントの株式会社テックアナリシス

【英文査読付原著論文】　（10件）

（１）H. Hisada, A. Okayama, T. Hoshino, J. Carriere, T. Koide, Y. Yamamoto, T. Fukami, “Determining the Distribution of Active Pharmaceutical Ingredients in Combination Tablets Using Near IR and Low-Frequency Raman Spectroscopy Imaging” Chemical and Pharmaceutical Bulletin, 68, 155–160 (2020). //New//

（2）M. Inoue, T. Osada, H. Hisada,, T. Koide, T. Fukami,, A. Roy. R. Heyler, “Solid-State Quantification of Cocrystals in Pharmaceutical Tablets Using Transmission Low-Frequency Raman Spectroscopy” Analytical Chemistry, 91, 13427-13432 (2019).

（3）R. Shimamura, T. Koide, H. Hisada, M. Inoue, T. Fukami, N Katori, Y. Goda, “Pharmaceutical quantification with univariate analysis using transmission Raman spectroscopy” Drug. Dev. Ind. Pharm., 45, 1430-1436 (2019).

（4）M. Inoue, H. Hisada, T. Koide, T. Fukami, A, Roy, J. Carriere, R. Heyler, “Transmission low-frequency Raman spectroscopy for quantification of crystalline polymorphs in pharmaceutical tablets” Anal. Chem., 91, 1997-2003 (2019).

（5）M. Azuma, M. Yoshimura-Fujii, M. Inoue, H. Hisada, T. Koide, M. Kemper, Y. Yamamoto, N. Suzuki, T. Suzuki; T. Fukami, “Molecular state of active pharmaceutical ingredients in ketoprofen dermal patches characterized by pharmaceutical evaluation” Biol. Pharm. Bull., 41, 1348-1354 (2018).

（6）M. Inoue, H. Hisada, T. Koide, J. Carriere, R. Heyler, T. Fukami, “Real-time formation monitoring of cocrystals with a different stoichiometry using probe-type low-frequency Raman spectroscopy” Industrial & Engineering Chemistry Research, 56, 12693-12697 (2017).

（7）M. Inoue , H. Hisada, T. Koide, J. Carriere, R. Heyler, T. Fukami, “In situ monitoring of crystalline transformation of carbamazepine using probe type low frequency Raman spectroscopy” Org. Process Res. Dev., 21, 262-265 (2017).

（8）T. Koide, T. Fukami, H. Hisada, M. Inoue, J. Carriere, R. Heyler, N. Katori, H. Okuda, Y. Goda “Identification of pseudopolymorphism of magnesium stearate by using low frequency Raman spectroscopy” Org. Process Res. Dev., 20, 1906-1910 (2016).

（9）T. Fukami, T. Koide, H. Hisada, M. Inoue, Y. Yamamoto, T. Suzuki, K. Tomono, “Pharmaceutical evaluation of atorvastatin calcium tablets available on the Internet: a preliminary investigation of substandard medicines in Japan” Journal of Drug Delivery Science and Technology, 31, 35-40 (2016).

（１0）H. Hisada, M. Inoue, T. Koide, J. Carriere, R. Heyler, T. Fukami, “Direct high-resolution imaging of crystalline components in pharmaceutical dosage forms using low-frequency Raman spectroscopy” Organic Process Research & Development, 19, 1796-1798 (2015).

【和文査読付原著論文】　（1件）

（１）久田浩史, 佐久間発, 大西優, 井上元基, 牟田史仁, 深水啓朗「日本薬局方の医薬品各条における確認試験を志向したラマン分光法の実用性」製剤機械技術学会誌 27(1), 5-12 (2018)

【招待・依頼講演 】

（１）M. Inoue, H. Hisada, T. Koide, T. Fukami, A. Roy, J. Carriere, R. Heyler “Quantification of crystalline active pharmaceutical ingredients by transmission low-frequency Raman spectroscopy” Scix2019, CA, US, October 13-18 2019

（2）M. Inoue, H. Hisada, T. Koide, T. Fukami, “Real-time monitoring of crystalline compounds using in situ low frequency Raman probe” Scix2016, MN, US, September 19-23 2016

【国際学会における発表】

（１）M. Inoue, H. Hisada, T. Koide, T. Fukami, A. Roy, J. Carriere, R. Heyler “Quantification of Polymorphs in Pharmaceutical Tablets using Transmission Low-Frequency Raman Spectroscopy” 3rd European Conference on Pharmaceutics, Bologna, Italy, March, 25-26, 2019

（2）M. Inoue, H. Hisada, T. Koide, J. Carriere, R. Heyler, T. Fukami “Evaluation of Carbamazepine Polymorphs in Solid Dosage Forms Using Low-Frequency Raman Spectroscopy” 2017 AAPS Annual Meeting, San Diego, US, November 12-15, 2017

（3）M. Inoue, H. Hisada, T. Koide, J. Carriere, R. Heyler, T. Fukami “In situ Crystallization monitoring using probe type low frequency Raman spectroscopy” 6th FIP Pharmaceutical Sciences World Congress 2017, Stockholm, Sweden, May 21-24, 2017

（4）T. Koide, H. Hisada, M. Inoue, T. Fukami, N. Katori, Y. Goda “Pharmaceutical quantification for content uniformity of solid dosage forms using Raman Spectroscopy” 2016AAPS, Colorado, USA, November, 13-17, 2016

（5）T. Fukami, M. Inoue, H. Hisada, T. Koide, “Pharmaceutical evaluation of atorvastatin calcium tablets available on the Internet”, Scix2016, MN, US, September 19-23 2016

（6）T. Fukami, M. Inoue, H. Hisada, T. Koide, “Chemical Imaging of Crystalline Components in Pharmaceutical Dosage Forms by Using Low Frequency Raman Spectroscopy” Scix2015, RI, USA, September 27-October2, 2015

【国内学会における発表】 　（一部抜粋，共著）

1)　「透過低波数ラマン分光法による結晶多形の定量」日本薬剤学会第33年会(静岡)2018年5月

2)　「プローブ型低波数ラマン分光器によるコクリスタル形成のモニタリング」日本薬剤学会第32年会(さいたま)2017年5月

3)　「低波数ラマン分光法を用いたシクロデキストリン包接複合体の分析」日本薬学会第137年会(仙台) 2017年3月

4)　「プローブ型低波数ラマン分光器による結晶転移のモニタリング」日本薬剤学会第31年会(岐阜)2016年5月

5)　「低波数ラマン分光法を用いた錠剤中原薬の結晶多形のイメージング」第32回製剤と粒子設計シンポジウム（豊橋）2015年10月